Lehane, Adele M : rechercher sur Z-Library

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1

Membrane transport in the malaria parasite and its host erythrocyte

Kirk, Kiaran, Lehane, Adele M.

Journal:

Biochemical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 5.43 MB

english, 2014

2

A polymorphic drug pump in the malaria parasite

Kevin J. Saliba, Adele M. Lehane, Kiaran Kirk

Journal:

Molecular Microbiology

Année:

2008

Langue:

english

Fichier:

PDF, 135 KB

english, 2008

3

Efflux of a range of antimalarial drugs and ‘chloroquine resistance reversers’ from the digestive vacuole in malaria parasites with mutant PfCRT

Adele M. Lehane, Kiaran Kirk

Journal:

Molecular Microbiology

Année:

2010

Langue:

english

Fichier:

PDF, 875 KB

english, 2010

4

MAM 2008 Oral Abstracts

Rowena E. Martin, Adele M. Lehane, Rosa V. Marchetti, Rhys Hayward, Kevin J. Saliba, Susan M. Howitt, Stefan Bröer, Kiaran Kirk

Journal:

International Journal for Parasitology

Année:

2008

Langue:

english

Fichier:

PDF, 830 KB

english, 2008

5

Common dietary flavonoids inhibit the growth of the intraerythrocytic malaria parasite

Adele M Lehane, Kevin J Saliba

Journal:

BMC Research Notes

Année:

2008

Langue:

english

Fichier:

PDF, 412 KB

english, 2008

6

Choline uptake into the malaria parasite is energized by the membrane potential

Adele M Lehane, Kevin J Saliba, Richard J.W Allen, Kiaran Kirk

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 192 KB

english, 2004

7

Degrees of chloroquine resistance in Plasmodium – Is the redox system involved?

Adele M. Lehane, Christopher A. McDevitt, Kiaran Kirk, David A. Fidock

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Année:

2012

Langue:

english

Fichier:

PDF, 383 KB

english, 2012

8

PfCRT and its role in antimalarial drug resistance

Andrea Ecker, Adele M. Lehane, Jérôme Clain, David A. Fidock

Journal:

Trends in Parasitology

Année:

2012

Langue:

english

Fichier:

PDF, 791 KB

english, 2012

9

Chlorpheniramine Analogues Reverse Chloroquine Resistance in Plasmodium falciparum by Inhibiting PfCRT

Deane, Karen J., Summers, Robert L., Lehane, Adele M., Martin, Rowena E., Barrow, Russell A.

Journal:

ACS Medicinal Chemistry Letters

Année:

2014

Langue:

english

Fichier:

PDF, 635 KB

english, 2014

10

Quinine Dimers Are Potent Inhibitors of the Plasmodium falciparum Chloroquine Resistance Transporter and Are Active against Quinoline-Resistant P. falciparum

Hrycyna, Christine A., Summers, Robert L., Lehane, Adele M., Pires, Marcos M., Namanja, Hilda, Bohn, Kelsey, Kuriakose, Jerrin, Ferdig, Michael, Henrich, Philipp P., Fidock, David A., Kirk, Kiaran, Ch

Journal:

ACS Chemical Biology

Année:

2014

Langue:

english

Fichier:

PDF, 950 KB

english, 2014

11

Diverse chemotypes disrupt ion homeostasis in the malaria parasite

Lehane, Adele M., Ridgway, Melanie C., Baker, Eileen, Kirk, Kiaran

Journal:

Molecular Microbiology

Année:

2014

Langue:

english

Fichier:

PDF, 951 KB

english, 2014

12

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium

Jiménez-Díaz, María Belén, Ebert, Daniel, Salinas, Yandira, Pradhan, Anupam, Lehane, Adele M., Myrand-Lapierre, Marie-Eve, O’Loughlin, Kathleen G., Shackleford, David M., Justino de Almeida, Mariana,

Journal:

Proceedings of the National Academy of Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2014

13

A lactate and formate transporter in the intraerythrocytic malaria parasite, Plasmodium falciparum

Marchetti, Rosa V., Lehane, Adele M., Shafik, Sarah H., Winterberg, Markus, Martin, Rowena E., Kirk, Kiaran

Journal:

Nature Communications

Année:

2015

Langue:

english

Fichier:

PDF, 581 KB

english, 2015

14

An acid-loading chloride transport pathway in the intraerythrocytic malaria parasite, Plasmodium falciparum

Henry, Roselani I., Cobbold, Simon A., Allen, Richard J. W., Khan, Asif, Hayward, Rhys, Lehane, Adele M., Bray, Patrick G., Howitt, Susan M., Biagini, Giancarlo A., Saliba, Kevin J., Kirk, Kiaran

Journal:

Journal of Biological Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 3.08 MB

english, 2010

15

1 H-NMR metabolite profiles of different strains of Plasmodium falciparum

Teng, Rongwei, Lehane, Adele M., Winterberg, Markus, Shafik, Sarah H., Summers, Robert L., Martin, Rowena E., van Schalkwyk, Donelly A., Junankar, Pauline R., Kirk, Kiaran

Journal:

Bioscience Reports

Année:

2014

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2014

16

Verapamil-sensitive transport of quinacrine and methylene blue via mutant PfCRT reduces the malaria parasite's susceptibility to these tricyclic drugs

van Schalkwyk, Donelly A., Nash, Megan N., Shafik, Sarah H., Summers, Robert L., Lehane, Adele M., Smith, Peter J., Martin, Rowena E.

Journal:

The Journal of Infectious Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 2.56 MB

english, 2015

17

Bacteriophage-encoded glucosyltransferase GtrII of Shigella flexneri : membrane topology and identification of critical residues

LEHANE, Adele M., KORRES, Haralambos, VERMA, Naresh K.

Journal:

Biochemical Journal

Année:

2005

Langue:

english

Fichier:

PDF, 421 KB

english, 2005

18

Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies

Veiga, M. Isabel, Dhingra, Satish K., Henrich, Philipp P., Straimer, Judith, Gnädig, Nina, Uhlemann, Anne-Catrin, Martin, Rowena E., Lehane, Adele M., Fidock, David A.

Journal:

Nature Communications

Année:

2016

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2016

19

A Forward-genetic Screen Identifies a Negative Regulator of Rapid Ca 2+ -dependent Cell Egress in the Intracellular Parasite Toxoplasma gondii

McCoy, James M, Stewart, Rebecca J, Uboldi, Alessandro D, Li, Dongdi, Schröder, Jan, Scott, Nichollas E, Papenfuss, Anthony T, Lehane, Adele M, Foster, Leonard J, Tonkin, Christopher J

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 8.33 MB

english, 2017

20

Cell swelling induced by the antimalarial KAE609 (cipargamin) and other PfATP4-associated antimalarials

Dennis, Adelaide S. M., Lehane, Adele M., Ridgway, Melanie C., Holleran, John P., Kirk, Kiaran

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2018

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2018

21

Diverse antimalarials from whole-cell phenotypic screens disrupt malaria parasite ion and volume homeostasis

Dennis, Adelaide S. M., Rosling, James E. O., Lehane, Adele M., Kirk, Kiaran

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 2.69 MB

english, 2018

22

Biochemical characterization and chemical inhibition of PfATP4-associated Na + -ATPase activity in Plasmodium falciparum membranes

Rosling, James E. O., Ridgway, Melanie C., Summers, Robert L., Kirk, Kiaran, Lehane, Adele M.

Journal:

Journal of Biological Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 630 KB

english, 2018

23

Defense Peptides Engineered from Human Platelet Factor 4 Kill Plasmodium by Selective Membrane Disruption

Lawrence, Nicole, Dennis, Adelaide S.M., Lehane, Adele M., Ehmann, Anna, Harvey, Peta J., Benfield, Aurélie H., Cheneval, Olivier, Henriques, Sónia Troeira, Craik, David J., McMorran, Brendan J.

Journal:

Cell Chemical Biology

Année:

2018

Langue:

english

Fichier:

PDF, 3.19 MB

english, 2018

24

Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii

Uboldi, Alessandro D., Wilde, Mary-Louise, McRae, Emi A., Stewart, Rebecca J., Dagley, Laura F., Yang, Luning, Katris, Nicholas J., Hapuarachchi, Sanduni V., Coffey, Michael J., Lehane, Adele M., Bott

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 15.70 MB

english, 2018

25

A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4

Gilson, Paul R., Kumarasingha, Rasika, Thompson, Jennifer, Zhang, Xinxin, Penington, Jocelyn Sietsma, Kalhor, Robabeh, Bullen, Hayley E., Lehane, Adele M., Dans, Madeline G., de Koning-Ward, Tania F.,

Journal:

Scientific Reports

Année:

2019

Langue:

english

Fichier:

PDF, 2.50 MB

english, 2019

26

A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4

Gilson, Paul R., Kumarasingha, Rasika, Thompson, Jennifer, Zhang, Xinxin, Penington, Jocelyn Sietsma, Kalhor, Robabeh, Bullen, Hayley E., Lehane, Adele M., Dans, Madeline G., de Koning-Ward, Tania F.,

Journal:

Scientific Reports

Année:

2019

Fichier:

PDF, 2.50 MB

2019